Medical Information, Questions or Concerns

During the Holiday season, please note that our Medical Information and Drug Safety service will be closed from December 23rd 2017 to January 1st 2018 inclusively. Our regular activities will resume on January 2nd, 2018. In case of an emergency, please seek immediate medical assistance or call 911.

Happy Holidays!

Duchesnay USA encourages you to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

You are welcome to either fill out our form below or call our Medical Information toll-free number at: 1 855 722-7734. (Medical Information service available in English only)

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Contact info

For general information:
Duchesnay USA Inc.
919 Conestoga Road
Building One, Suite 203
Rosemont, PA USA 19010
Telephone: (484) 380-2641
Toll-free: 1 (888) 559-2188
Fax: (484) 380-2658
For Medical Information, Questions or Concerns:
To reach our medical information service, click here
To contact Canadian affiliate:
flag canada Duchesnay Inc.
950, boul. Michèle-Bohec
Blainville QC Canada J7C 5E2
Telephone: (450) 433-PREG (7734) or 1 (877) 833-PREG (7734)
Fax: (450) 433-2211 or 1 (888) 588-8508

Indication and Important Safety Information


Diclegis® is a prescription medicine used to treat nausea and vomiting of pregnancy in women who have not improved with change in diet or other non-medicine treatments.

Limitations of Use

Diclegis® has not been studied in women with hyperemesis gravidarum.

Important Safety Information

Do not take Diclegis® if you are allergic to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any of the ingredients in Diclegis®. You should also not take Diclegis® in combination with medicines called monoamine oxidase inhibitors (MAOIs), as these medicines can intensify and prolong the adverse central nervous system (CNS) effects of Diclegis®.

The most common side effect of Diclegis® is drowsiness. Do not drive, operate heavy machinery, or other activities that need your full attention unless your healthcare provider says that you may do so.

Do not drink alcohol, or take other CNS depressants such as cough and cold medicines, certain pain medicines, and medicines that help you sleep while you take Diclegis®. Severe drowsiness can happen or become worse causing falls or accidents.

Diclegis® should be used with caution in women who have certain medical conditions, such as asthma, or eye, stomach or bladder problems. Tell your healthcare provider about all of your medical conditions so he/she can assess if Diclegis® is right for you.

It is not known if Diclegis® is safe and effective in children under 18 years of age. Keep Diclegis® and all medicines out of the reach of children.

Diclegis® is a delayed-release formulation, so signs of overdose may not appear right away. If you take too much Diclegis (overdose), you may have the following symptoms: restlessness, dry mouth, the pupils of your eyes become larger (dilated), sleepiness, dizziness, confusion, fast heart rate, seizures, muscle pain or weakness, and sudden and severe kidney problems. If you have these symptoms and they are severe, they may lead to death. Stop taking Diclegis, call your healthcare provider or go to the nearest hospital emergency room right away. For more information about overdose treatment, call your poison control center at 1-800-222-1222.

Diclegis® is intended for use in pregnant women.

Tell your healthcare provider about all of your medical conditions, including if you are breastfeeding or plan to breastfeed. Diclegis® can pass into your breast milk and may harm your baby. You should not breastfeed while using Diclegis®.

Duchesnay USA encourages you to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Tablets shown throughout the site are not actual size.


Please click here for full Prescribing Information and Patient Information.

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