Diclegis® is accessible and affordable

We make it easy for you to write Diclegis®

There are several ways to help you provide Diclegis® to all your patients. Even without prescription drug insurance or coverage for Diclegis®, your patients could pay as little as $1 per tablet.

My patient has commercial insurance and Diclegis® is covered

Use the Copay Savings Card

With this card, most patients could pay as little as
$0* for a prescription of Diclegis®

Patients simply show the Copay Savings Card information below to their pharmacist:

copay information

  • The code may be entered manually when patients pick up their prescription to ensure that they pay the lowest price.
  • Have an EMR system? Simply add the Copay information above to your system and the universal code can be used for all your Diclegis® patients.

Click to download and print your Copay Savings Card.


Make sure your patient’s pharmacist has entered your code so that she pays the lowest price!

If you have any questions about the Diclegis® Savings card, please call 1-800-250-5195.

*Download Copay Savings Card to see terms and conditions.

My patient doesn’t have insurance or Diclegis® is not covered by their insurance

ProCare Pharmacy Care ships right to your patient’s home!

With ProCare Pharmacy Care, patients can receive Diclegis® for just
$1 per tablet!

  • 60 tablets for $60, free shipping
  • 90 tablets for $90, free shipping
  • 120 tablets for $120, free shipping

Prescribe Diclegis® through ProCare Pharmacy Care, Miramar, Florida 33025 (NABP/NCPDP Provider ID: 1098121)

Fax, call in or e-prescribe now!

Download the instructions and order form.


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If you have any questions, please call the ProCare Pharmacy Care at 1-877-291-1122

Indication and Important Safety Information


Diclegis® is a fixed-dose combination drug product of 10 mg doxylamine succinate, an antihistamine, and 10 mg pyridoxine hydrochloride, a vitamin B6 analog, indicated for the treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management.


Diclegis® has not been studied in women with hyperemesis gravidarum.



Diclegis® is contraindicated in women with any of the following conditions:

  • Known hypersensitivity to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any inactive ingredient in the formulation;
  • Monoamine oxidase (MAO) inhibitors intensify and prolong the adverse central nervous system effects of Diclegis®.

Warnings and Precautions:

  • Somnolence: Diclegis® may cause somnolence due to the anticholinergic properties of doxylamine succinate, an antihistamine. Women should avoid engaging in activities requiring complete mental alertness, such as driving or operating heavy machinery, while using Diclegis® until cleared to do so by their healthcare provider.
  • Central nervous system (CNS) depressants: Use of Diclegis® is not recommended if a woman is concurrently using CNS depressants, such as alcohol or sedating medications, including other antihistamines (present in some cough and cold medications), opiates, and sleep aids. The combination of Diclegis® and CNS depressants could result in severe drowsiness leading to falls or other accidents.
  • Concomitant Medical Conditions: Use Diclegis® with caution in women with (1) asthma, (2) increased intraocular pressure, (3) narrow angle glaucoma, (4) a stenosing peptic ulcer, (5) pyloroduodenal obstruction, or (6) bladder-neck obstruction.
  • Interference with Urine Screen for Methadone, Opiates and Phencyclidine Phosphate (PCP): There have been reports of false positive urine screening tests for methadone, opiates, and PCP with doxylamine succinate/pyridoxine hydrochloride use. Women should be informed that use of Diclegis® may result in false positive urine drug screening for methadone, opiates and PCP.

Adverse Reactions: The most common adverse reaction (≥5 percent and exceeding the rate in placebo) with combination 10 mg doxylamine succinate and 10 mg pyridoxine hydrochloride tablets is somnolence.

Drug-Food Interactions: A food-effect trial demonstrated that the delay in the onset of action of Diclegis® may be further delayed, and a reduction in absorption may occur when tablets are taken with food. Therefore, Diclegis® should be taken on an empty stomach with a glass of water.

Use in Specific Populations:

  • Pregnancy: Diclegis® is intended for use in pregnant women.
  • Lactation: Women should not breastfeed while using Diclegis® because the antihistamine component (doxylamine succinate) in Diclegis® can pass into breast milk. Excitement, irritability, and sedation have been reported in nursing infants presumably exposed to doxylamine succinate through breast milk. Infants with apnea or other respiratory syndromes may be particularly vulnerable to the sedative effects of Diclegis® resulting in worsening of their apnea or respiratory conditions.
  • Pediatric Use: The safety and effectiveness of Diclegis® in children under 18 years of age have not been established. Fatalities have been reported from doxylamine overdose in children. Children appear to be at a high risk for cardiorespiratory arrest.

Overdosage: Diclegis® is a delayed-release formulation; therefore, signs and symptoms of intoxication may not be apparent immediately. Signs and symptoms of overdose may include restlessness, dryness of mouth, dilated pupils, sleepiness, vertigo, mental confusion, and tachycardia. At toxic doses, doxylamine exhibits anticholinergic effects, including seizures, rhabdomyolysis, acute renal failure and death. If treatment is needed, it consists of gastric lavage or activated charcoal, whole bowel irrigation and symptomatic treatment. If you suspect an overdose or seek additional information about overdose treatment, call a poison control center at 1-800-222-1222.

To report suspected adverse reactions, contact Duchesnay Inc. at 1-855-722-7734 or medicalinfo@duchesnayusa.com or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.


eVoucherRx™ Program

As a participant in the eVoucherRx Program powered by RelayHealth, Duchesnay USA has made it possible to extend prescription savings on to you. eVoucherRx is a paperless electronic coupon program that makes co-pay savings on your prescription for Diclegis® easy for physicians, patients and pharmacists.

Participating Pharmacies

Patients simply take your eligible prescription for Diclegis® to a participating pharmacy and the eVoucherRx savings coupon will be automatically applied to your co-pay.

Find an eVoucherRx™ pharmacy in your area:

The eVoucherRx™ program, powered by RelayHealth, provides electronic coupons to help reduce a patient's out-of-pocket cost on selected products. Participating pharmacies are subject to change without notice.



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